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Furthermore, in a phase II study, the combination of chemotherapy (albumin-bound paclitaxel and gemcitabine) along with pegvorhyaluronidase alfa (PEGPH20), an agent designed to degrade hyaluronan, has been shown to improve progression-free survival in pancreatic cancer patients, especially those with hyaluronan-high tumors [136]
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
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CrossRef Enhanced STEAP4 Ubiquitination in Obesity: Insights From Combined Proteome and Ubiquitylome Analysis of Visceral Adipose Tissue Yuhao Li, Jie Li, Genyao Wang, Shushu Yang, Dong Liu, Hao Wen, Mengjun Zhang, Chengjie Duan, Meiling Yu, Shufeng Wang, Sheng Guo, Xiaoling Chen, Li Wang Molecular & Cellular Proteomics.2026
In Phase II detoxification, the liver attaches a glutathione molecule to a toxin, making it water-soluble so it can be safely flushed out of the system
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